Construction and evaluation of measures of identification of sound elements in words in kindergarten,

Thesis (M.A.)--Boston Universit

Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery

Abstract—The robust identification and measurement of the intima media thickness (IMT) has a high clinical relevance because it represents one of the most precise predictors used in the assessment of potential future cardiovascular events. To facilitate the analysis of arterial wall thickening in serial clinical investigations, in this paper we have developed a novel fully automatic algorithm for the segmentation, measurement, and tracking of the intima media complex (IMC) in B-mode ultrasound video sequences. The proposed algorithm entails a two-stage image analysis process that initially addresses the segmentation of the IMC in the first frame of the ultrasound video sequence using a model-based approach; in the second step, a novel customized tracking procedure is applied to robustly detect the IMC in the subsequent frames. For the video tracking procedure, we introduce a spatially coherent algorithm called adaptive normalized correlation that prevents the tracking process from converging to wrong arterial interfaces. This represents the main contribution of this paper and was developed to deal with inconsistencies in the appearance of the IMC over the cardiac cycle. The quantitative evaluation has been carried out on 40 ultrasound video sequences of the common carotid artery (CCA) by comparing the results returned by the developed algorithm with respect to ground truth data that has been manually annotated by clinical experts. The measured IMTmean ± standard deviation recorded by the proposed algorithm is 0.60 mm ± 0.10, with a mean coefficient of variation (CV) of 2.05%, whereas the corresponding result obtained for the manually annotated ground truth data is 0.60 mm ± 0.11 with a mean CV equal to 5.60%. The numerical results reported in this paper indicate that the proposed algorithm is able to correctly segment and track the IMC in ultrasound CCA video sequences, and we were encouraged by the stability of our technique when applied to data captured under different imaging conditions. Future clinical studies will focus on the evaluation of patients that are affected by advanced cardiovascular conditions such as focal thickening and arterial plaques

Nomogram for the Evaluation of Blackbody Radiancy and of Peak and Total Intensities for Spectral Lines with Doppler Contour

A nomogram has been constructed for the determination of blackbody radiancy and of peak and total intensities for spectral lines with Doppler contour. The basic equations used for the construction of the nomogram and the use of the nomogram are described briefly. A method is outlined for determining absolute values of total intensities for spectral lines with combined Doppler and resonance contour by using the nomogram in conjunction with the “curves of growth.

Evaluation of novel depressed collector for linear-beam microwave tubes

Evaluation tests to demonstrate feasibility of increasing efficiency of linear beam microwave tubes using novel depressed collecto

Combined EISCAT radar and optical multispectral and tomographic observations of black aurora

Black auroras are recognized as spatially well-defined regions within a uniform diffuse auroral background where the optical emission is significantly reduced. Black auroras typically appear post-magnetic midnight and during the substorm recovery phase, but not exclusively so. We report on the first combined multimonochromatic optical imaging, bistatic white-light TV recordings and incoherent scatter radar observations of black aurora by EISCAT of the phenomenon. From the relatively larger reduction in luminosity at 4278 Å than at 8446 Å we show that nonsheared black auroras are most probably not caused by downward directed electrical fields at low altitude. From the observations, we determine this by relating the height and intensity of the black aurora to precipitating particle energy within the surrounding background diffuse aurora. The observations are more consistent with an energy selective loss cone. Hence the mechanism causing black aurora is most probably active in the magnetosphere rather than close to Earth

Phase linearity of the 914H coupled-cavity traveling wave tube

Tests of phase deviation from linearity were made on two 914H coupled-cavity traveling wave tubes (TWT). One tube had a voltage standing wave ratio (VSWR) of 2.4 and the other 1.4. The data showed that phase deviation is primarily a function of the amplitude and shape of the output VSWR. It was predicted that the low-VSWR tube would give a better system performance than the tube with a high VSWR. This prediction was confirmed by the Advanced Communications Technology Satellite (ACTS) system tests performed at the NASA Lewis Research Center. A possible improvement in the construction and stability of coupled-cavity TWT's is discussed

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin

Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components. One such protein is the Y-box transcription factor ZONAB/DbpA that binds to ZO-1, a component of the junctional plaque. Symplekin, another nuclear protein that can associate with tight junctions, functions in the regulation of polyadenylation and thereby promotes gene expression. Here, we addressed the question of whether these two proteins interact and whether this is of functional relevance. We demonstrate that ZONAB/DbpA and symplekin form a complex in kidney and intestinal epithelial cells that can be immunoprecipitated and that exists in the nucleus. The interaction between ZONAB/DbpA and symplekin can be reconstituted with recombinant proteins. In reporter gene assays in which ZONAB/DbpA functions as a repressor, symplekin functionally interacts with ZONAB/DbpA, indicating that symplekin can also promote transcriptional repression. RNAi experiments indicate that symplekin depletion reduces the nuclear accumulation and the transcriptional activity of ZONAB/DbpA in colon adenocarcinoma cells, resulting in inhibition of proliferation and reduced expression of the ZONAB/DbpA-target gene cyclin D1. Our data thus indicate that symplekin and ZONAB/DbpA cooperate in the regulation of transcription, and that they promote epithelial proliferation and cyclin D1 expression